South African govt ordered to provide HIV drug to mothers - now

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The High Court in Pretoria yesterday (11 March) ordered the South African national and provincial governments to provide nevirapine to all HIV-positive pregnant women for prevention of mother to child tranmission.

Judge Chris Botha reiterated the High Court ruling of December 2001 which mandated the South African authorities to provide nevirapine, a ruling which the government appealed, questioning the validity of the court's ruling. Although Judge Botha will allow the appeal to go to South Africa's Constitutional Court, he ruled that nevirapine must be made available to all HIV-positive pregnant women at public health facilities "with the capacity for testing and counselling", while the appeal is pending.

In his hard-hitting ruling Judge Botha said that he believed that the government's appeal was "unlikely" to prove successful, adding that they would, at most, be granted a modification on the original order. If the government's appeal were to prove successful he said that they would have suffered little more than "inconvenience", which "ethically motivated health workers will gladly assume."

Glossary

capacity

In discussions of consent for medical treatment, the ability of a person to make a decision for themselves and understand its implications. Young children, people who are unconscious and some people with mental health problems may lack capacity. In the context of health services, the staff and resources that are available for patient care.

pilot study

Small-scale, preliminary study, conducted to evaluate feasibility, time, cost, adverse events, and improve upon the design of a future full-scale research project.

 

exclusion criteria

Defines who cannot take part in a research study. Eligibility criteria may include disease type and stage, other medical conditions, previous treatment history, age, and gender. For example, many trials exclude women who are pregnant, to avoid any possible danger to a baby, or people who are taking a drug that might interact with the treatment being studied.

mother-to-child transmission (MTCT)

Transmission of HIV from a mother to her unborn child in the womb or during birth, or to infants via breast milk. Also known as vertical transmission.

However he added that should he suspend the original order to provide nevirapine and the government case were to fail "it is manifest that it will result in the loss of lives that could have been saved. It would be odious to calculate the number of lives that one could consider affordable in order to save [the government] the sort of inconvenience they foreshadow. I find myself unable to formulate a motivation for tolerating preventable deaths for the sake of sparing [the government] prejudice that cannot amount to much more than organisational inconvenience."

So far the South African government has only provided nevirapine to HIV-positive pregnant women at 18 state hospitals as part of a trial, a policy which is now looking unsustainable, particularly as a government-commissioned report published last week said that nevirapine programmes in state-run health facilities were viable and should be commenced nationwide as soon as possible.

Nevertheless a health ministry spokesperson reacted to Judge Botha's ruling saying: "If [Judge Botha] says we should implement without support mechanisms, it is a matter of concern" adding that the 18 pilot sites had experienced problems in the administration of the drug.

Treatment activists have welcomed the ruling, with a spokesperson for the Treatments Action Campaign saying "We believe that Judge Chris Botha has put morality back into law and policy by putting people's lives first."

Excluded from the ruling are the governments of Western Cape and KwaZulu- Natal which already supply nevirapine at public health facilities. Three other provincial governments have also declared declared their intention to initiate nevirapine programmes.