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Cumulative viral load: an important measure of risk of death in patients with HIV

Low but detectable viral load during HIV treatment involves a risk of resistance

Confirmatory viral load reduces HIV treatment switches fourfold in 6-country African study

Elevated CD8 cell count associated with HIV treatment failure

At least one in six patients maintains a viral load over one hundred thousand

Treatment monitoring: no clear benefit to adding viral load to CD4 or clinical symptoms in Thailand and Africa

A lab technician at work in Uganda. Diagnostic equipment in rural health centres is often rudimentary. AMREF is helping to upgrade labs in Kiboga and Luwero districts. Image ©AMREF www.amrefuk.org

Nevirapine rather than efavirenz-based HIV treatment more likely to suppress viral load to zero

HIV detectable in CSF of 10% of patients taking successful antiretroviral treatment

Most patients in darunavir monotherapy trial stay fully suppressed